Conventional classroom-based education has been utilized for decades. While time-tested, the approach can sometimes be limiting, especially by confining students to their classroom when they need experience in dealing with problems in diverse environments. During Problem-Based Learning sessions (PBL), for example, solely utilizing the classroom environment, which is often based on theoretical learning, ultimately limits their creative and practical abilities to solve complex One Health problems. To address this limitation, Professor Dr. Mohd. Hezmee Mohd Noor and Dr. Tengku Rinalfi Putra Tengku Azizan from the Faculty of Veterinary Medicine at the University of Putra Malaysia had the bold idea to take PBL out of the classroom and put it into the real world to better serve student’s needs. As such, they developed the “In Situ One Health PBL” learning model. In Situ One Health PBL allows the students to engage more fully by bringing them to relevant locations with real world applicability to better understand the issues and challenges faced by One Health practitioners.